Histochemistry. VII. Flavones in Scutellariae Radix.

Antiradical and antioxidant activity of flavones from Scutellariae baicalensis radix.

We evaluated the antioxidant properties of four main flavones from Scutellaria baicalensis: baicalein, wogonin and their glucuronides - baicalin and wogonoside. We used three in vitro assays: free radical scavenging with 2,2'-diphenylpicrylhydrazyl radical, transition metal ions reducing power by phosphomolybdenum assay and inhibition of the hydroxyl radical-induced peroxidation of linoleic aci...

Flavones Isolated from Scutellariae radix Suppress Propionibacterium Acnes-Induced Cytokine Production In Vitro and In Vivo.

Scutellariae radix, the root of Scutellaria baicalensis, has long been applied in traditional formulations and modern herbal medications. Propionibacterium acnes (P. acnes) in follicles can trigger inflammation and lead to the symptom of inflammatory acnes vulgaris. This study was aimed at evaluating the effect of Scutellariae radix extract and purified components isolated from it on inflammati...

Inhibition of three novel Radix Scutellariae extracts on immediate hypersensitivity.

BACKGROUND Radix Scutellariae, a few papers reported its pharmacology activities including alleviate small intestines smooth muscles spasm, sedation, antihypertensive effect. However, the inhibition of its different organic extracts on immediate hypersensitivity has not bee researched. MATERIALS AND METHODS To investigate the anti-immediate hypersensitivity of three extracts including ethanol...

A comparative study of excretion of the components after oral administra- tion of pure baicalin radix scutellariae and scutellariae-paeoniae couple extracts to normal and ulcerative colitis rats

Radix scutellariae and Scutellariae-Paeoniae couple extracts are the well-known Traditional Chinese Medicine (TCM) to treat ulcerative colitis. Baicalin, wogonoside, baicalein and wogonin are the main effective ingredients in Radix scutellariae. This study was carried out to investigate the excretion profiles of baicalin, wogonoside, baicalein and wogonin in urine and feces after oral administr...

Pharmacokinetics and Pharmacodynamics Interaction between Oseltamivir and Radix Scutellariae in Sprague Dawley Rats